Scientists are still actively trying to understand neurodevelopmental disorders, but one thing has become clear: Genetic markers are not the only factors influencing their risk.
ADARs and Site-Directed RNA Editing as a Potential Therapeutic
by SeHee Park
In humans, Adenosine (A) to Inosine (I) conversion within RNA is mediated by deaminase enzymes known as ADARs (Adenosine deaminases acting on dsRNA). This change in RNA component by ADARs has numerous effects on biological pathways as discussed in my previous blog, "How Does RNA Editing Affect Human Health?".
Advanced genome editing tools improve our ability to cut and repair the defective genes responsible for various diseases in human beings, along with the generation of animal models and agricultural applications. Now the questions are, how does genome editing work? What are the platforms and applications? What are the challenges faced?
Over the last ~5-10 years, the biomedical field has seen a revolution in biologics through the use of antibody therapeutics. In this blog, I wanted to discuss what antibodies are, how the immune system uses them to combat infections, and how we use them for medical applications and therapeutics.
Biomarker Development: A Tool to Prevent Neurodegenerative Disorders
By Marwa Zafarullah
Identification and validation of reliable biomarkers can improve diagnosis, monitor therapeutic response, and guide the development of targeted therapies for neurodegenerative disorders. Now the questions are, what are these biomarkers? How can we develop them? What are the challenges faced?
With cases on the rise, I want to discuss some of the biggest questions on everyone’s mind when it comes to the COVID-19 vaccine. When will a COVID-19 vaccine be available? What is the science behind the vaccine technology? And how safe will it be once its ready?
Biotechnology: Leading the Search for a Cure for COVID-19
by Jonas Calsbeek
Developing a test, therapy, or vaccine is an expensive process, and success is not guaranteed. What role does research in biotechnology play in helping to expedite this process in modern times?