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(Disclaimer: This blog is not intended as medical advice. Please consult a medical doctor if you are considering taking any new medicines or supplements. Mimio Health has their own disclaimer statements on their product packaging and at the bottom of their home page, which emphasize that their product is not intended to treat or cure disease.)

The development of mRNA vaccines against COVID-19 has showcased the potential of RNA-based approaches, generating significant enthusiasm and investment in the field. RNA-based therapeutics offer new potential treatments for a range of diseases, taking advantage of the natural role of RNA in gene expression and allowing for targeted gene regulation and protein synthesis. In this blog, we will explore the types of RNA-based therapeutics, their advantages and limitations, and the current state of research in the field. But first, let’s define what an RNA molecule is.

In an unmarked space in the Eastern suburbs of Davis, a biotechnology startup and its group of researchers are participating in advancing the future of sustainable food.

This is Part 3 of a three-part series on biological applications of microfluidic devices. Part 1 covered the history, physics, and popular fabrication methods of microfluidic devices, while Part 2 discussed the application of microfluidic devices in low resource and point-of-care applications.

DNA damage is a phenomenon that can be detrimental to genomic integrity. Thankfully, our bodies have adapted many pathways to repair such DNA damage to prevent mutagenesis and cell death. There are many different topics related to DNA damage and repair, and I have recently focused on two other interesting topics related to this. In my first blog, I touched on the epigenetic role of DNA damage.

“Don’t smoke.”

In this day and age, we have all heard this refrain over and over from a very young age. From the high taxes on cigarettes and other tobacco products to the no-smoking public campaigns, it’s been drummed into heads (and our wallets) that smoking is bad for us.  But why is it so bad? And why do so many people smoke anyway knowing that it’s bad for them?

The brain is a complex organ that controls every physical movement we have or ever will make and houses our sense of self.  As merely on average 3-pound organ, the brain is somehow able to govern all our sensory input coming from sight, smell, touch, taste, and hearing and assemble messages in a way that directs our thoughts, speech, movement, and internal organ functions.

There have been many methods developed for the measurement of DNA repair in a “test tube.” While these methods are powerful to reveal DNA repair capacity, it is limited by the fact that the complexities of the cell are not considered.

This is Part 2 of a 3-part series on biological applications of microfluidic devices. Part 1 covered the history, physics, and popular fabrication methods of microfluidic devices. This part will cover the application of microfluidic devices in low resource and point-of-care applications, while Part 3 will discuss the role of microfluidic devices in cutting edge technologies.

Extracellular vesicles (EVs) are small membranous nanoparticles secreted by all types of cells and can be found in numerous bodily fluids, including blood, urine, cerebrospinal fluid, and more. For years, scientists believed that it functioned more as a waste disposal system for cells, carrying unwanted molecules and metabolites out of the cell and into circulation to be cleared out. But it turns out that one cell’s trash could be another cell’s treasure.