Human & Animal Health

Extracellular vesicles (EVs) are small membranous nanoparticles secreted by all types of cells and can be found in numerous bodily fluids, including blood, urine, cerebrospinal fluid, and more. For years, scientists believed that it functioned more as a waste disposal system for cells, carrying unwanted molecules and metabolites out of the cell and into circulation to be cleared out. But it turns out that one cell’s trash could be another cell’s treasure.

Repairing DNA damage is an essential capability for humans and other multicellular organisms. Inability to repair DNA damage can lead to cells dividing randomly and the development of both benign and malignant tumors. The David Lab at UC Davis is working on understanding the molecular mechanisms of DNA repair as a first step in developing targeted therapies to prevent common cancers.

by Chidera Alim

For good context and background, be sure to go through the first part of the series, Moments That Make the Beat Go On: Part 1.

by Chidera Alim

by Bianca Yaghoobi

Polychlorinated biphenyls (PCBs) continue to be an environmental health concern after many thought the problem had been solved.

by Zach Bendiks

by Bianca Yaghoobi

Scientists are still actively trying to understand neurodevelopmental disorders, but one thing has become clear: Genetic markers are not the only factors influencing their risk.

by SeHee Park

by SeHee Park

In humans, Adenosine (A) to Inosine (I) conversion within RNA is mediated by deaminase enzymes known as ADARs (Adenosine deaminases acting on dsRNA). This change in RNA component by ADARs has numerous effects on biological pathways as discussed in my previous blog, "How Does RNA Editing Affect Human Health?".

by Zach Bendiks