ADARs and Site-Directed RNA Editing as a Potential Therapeutic
by SeHee Park
In humans, Adenosine (A) to Inosine (I) conversion within RNA is mediated by deaminase enzymes known as ADARs (Adenosine deaminases acting on dsRNA). This change in RNA component by ADARs has numerous effects on biological pathways as discussed in my previous blog, "How Does RNA Editing Affect Human Health?".