genome editing

The Future of Medicine: Gene Therapy and Its Applications

Tall or short? Blue irises or brown? Human genetic material, or deoxyribonucleic acid (DNA), include genes that provide cellular machinery with instructions to produce functional proteins. These proteins ultimately determine many traits and support our daily activities. However, due to cell aging or environmental exposure to chemicals or radiation, mutations can happen randomly within trait-encoding genes, leading to problematic gene expression and protein activity (Figure 1).

How Can We Cut and Repair Defective Genes?

How Can We Cut and Repair the Defective Genes?

by Marwa Zafarullah

Advanced genome editing tools improve our ability to cut and repair the defective genes responsible for various diseases in human beings, along with the generation of animal models and agricultural applications. Now the questions are, how does genome editing work? What are the platforms and applications? What are the challenges faced?