ADAR

ADAR Inhibitors - Future Cancer Therapeutics

In recent years, the field of cancer research has witnessed a growing interest in targeting RNA editing as a potential therapeutic strategy. Adenosine Deaminase Acting on RNA (ADAR), a key enzyme involved in RNA editing, has emerged as an attractive target for cancer therapy. In this blog post, we will explore the role of ADAR and RNA editing in cancer and the potential of ADAR inhibitors as effective cancer therapeutics, highlighting the progress made in this area and the challenges that lie ahead.

RNA Editing Affects Repair of DNA Damage by the NEIL Enzyme

DNA damage is a phenomenon that can be detrimental to genomic integrity. Thankfully, our bodies have adapted many pathways to repair such DNA damage to prevent mutagenesis and cell death. There are many different topics related to DNA damage and repair, and I have recently focused on two other interesting topics related to this. In my first blog, I touched on the epigenetic role of DNA damage.